Nano liquid chromatography columns

Microfabricated pillar array columns for liquid chromatography

Separation of tocopherols by nano-liquid chromatography.

Nanoliquid chromatography (nano-LC) was used for the separation of tocopherols (delta-, gamma-, alpha-TOH), alpha-tocopherol acetate (alpha-TOH-Ac) and an antioxidant compound, namely butylated hydroxytoluene (BHT) used to prevent TOHs autoxidation. The separation was carried out in a fused silica capillary of 100 microm I.D. and 375 microm O.D. packed in our laboratory with RP18 silica station...

Recent advances in high-performance liquid affinity chromatography columns.

High-performance liquid affinity chromatography (h.p.1.a.c.) is the term applied to the application of h.p.1.c. to affinity chromatography (Ohlson et al., 1978). Until recently affinity chromatography supports were unsuitable for use in high-performace applications. It is only in the last 8 years that these problems have been overcome, resulting in a second generation of affinity systems. The a...

3D printed metal columns for capillary liquid chromatography.

Coiled planar capillary chromatography columns (0.9 mm I.D. × 60 cm L) were 3D printed in stainless steel (316L), and titanium (Ti-6Al-4V) alloys (external dimensions of ~5 × 30 × 58 mm), and either slurry packed with various sized reversed-phase octadecylsilica particles, or filled with an in situ prepared methacrylate based monolith. Coiled printed columns were coupled directly with 30 × 30 m...

Troubleshooting Liquid-liquid Extraction Columns

Process engineers can be faced with the task of understanding and optimizing the performance of an existing liquid-liquid extraction (extraction) column. Often times, an extraction column has been operating many years, and the performance is not well understood by the personnel responsible for its operation. Since this technology is not treated comprehensively during most under-graduate Chemica...